بررسی وضعیت ایمنی سرخجه زنان در سن بارداری استان مازندران در سال های 78-79

Background and purpose: Rubella is a viral disease, which occurs in children and adolescents. Rubella infection in gestation period, in a person sensitive to this disease, can lead to serious complication in the fetus. Such as mortality and abortion and serious congorited disorders (congenital rubella syndrome). Ïnfection with rubella causes permanent immunity. Ând immunoglobulins essay of ÏgG as an indicator for the determination of immunity in the patients. Since rubella vaccination is not common in Ïran, hence we decided to determine the immunological status in the pregnant women infected with rubella virus in mazandaran province. Materials and Methods: The population who underwent our studying were 1420 girls about to get married referring to the health center laboratory for certain tests. This research is cross sectional study. The samples were collected by simple randomized method. 8 cities of the province were selected randomly the number of collecting samples were decided according to the estimated population of the cities taken in 1998 them the titer of ÏgG against rubella infection was measured by Ë L, & Â and the corded as positive for (the presence of antibody known as resistant) and negative (without of antibody, known as sensitive). Results: From the total number of 1420 causes under investigation. 109 (11.5.4.9) were sensitive to rubella on the basis of geological area and 1311 (92.3%) were resistant the percentage of sensitive cases were as follow 6.2, 10.25, 4.9, 5.55, 5.6, 5.1 and 8.9 in the cities of Babol and amol, sari, noshahr, behshahr, ramsar and noor respectively. Çonclusion: Çonsidering the sensitivity of 7% of the females in the pregnancy age group to rubella in this province and the risk of getting in the gestation period, and subsequently, due to endimicits of this disease in the region and the problem of clinical diagnosis vaccination of all the girls prior to their gestation period is recommenden, specially in the curly of life.